Wobbly Hedgehog Syndrome (WHS)

Causes, Treatment, and Prevention

Hedgehog rolling in grass.

Getty Images / praisaeng

Hedgehogs are unique pets that have unique health issues like wobbly hedgehog syndrome (WHS). Owners of both European and African hedgehogs should be aware of the symptoms of this degenerative neurological disease, including muscle weakness, difficulty moving, and paralysis. Hedgehogs may live up to two years after the onset of symptoms, but the disease is ultimately fatal.

What Is Wobbly Hedgehog Syndrome?

Wobbly hedgehog syndrome, also known as demyelinating paralysis, is a progressive disease that affects about one out of ten hedgehogs. It, unfortunately, leads to eventual paralysis and death due to the effects it has on the brain. It is classified as a neurological disease and affects the cerebrum, cerebellum, brain stem, and spinal cord of a hedgehog.

Symptoms of Wobbly Hedgehog Syndrome


  • Falling over
  • Muscle weakness
  • Difficulty walking
  • Wobbling when standing still
  • Paralysis
  • Seizures
  • Head tilt
  • Circling
  • Weight loss
  • Aggression
  • Urine retention
  • Intestinal stasis
  • Difficulty swallowing
  • Death

Wobbly hedgehog syndrome is named for the characteristic wobble that hedgehogs often display with this disease, even when they are standing still. Muscle weakness and a host of other neurological signs may occur as a result of changes in the brain and spinal cord, but there are other signs you may notice in your pet.

Behavioral changes, such as aggression, may accompany neurological degeneration. A hedgehog may lose its appetite, have difficulty swallowing food and water, retain stool and urine, and drop weight. These are all signs of its system breaking down. Paralysis is likely WHS progresses, and death is inevitable.

Causes of Wobbly Hedgehog Syndrome

Unfortunately, no one knows what causes wobbly hedgehog syndrome, but there are some speculations, including:

  • Genetics
  • Diet
  • Myelinopathy with central nervous system involvement
  • Kidney disease
  • Liver disease
  • Obesity

Diagnosing Wobbly Hedgehog Syndrome

Most hedgehogs with wobbly hedgehog syndrome are diagnosed based on their symptoms while they are alive. Blood tests to look at the kidney, liver, and bladder health, as well as x-rays, are commonly performed to see if other diseases are also present, but there is no test to specifically identify WHS.

Once a hedgehog passes away, a necropsy can be performed to know for sure whether it had WHS. A biopsy of the brain tissue can be analyzed and special stains can be used to look for the lesions that wobbly hedgehog syndrome causes.


Wobbly hedgehog syndrome has no effective treatment options, so supportive care is all that can be offered to a hedgehog with this disease. Ensuring the hedgehog can access its food and water and stay clean is of utmost importance to its quality of life. Once a hedgehog has degenerated significantly, euthanasia will be recommended.

Prognosis for Hedgehogs with Wobbly Hedgehog Syndrome

Unfortunately, wobbly hedgehog syndrome is fatal. Hedgehogs diagnosed with WHS typically live less than two years after the first signs of the disease are noted and are usually less than two years of age when the symptoms begin.

How to Prevent Wobbly Hedgehog Syndrome

If a hedgehog shows signs of WHS, it should not be bred. Since the most likely cause of this fatal disease is genetics, ensuring a hedgehog with WHS does not pass on these genes is the best way to prevent the disease from occurring in its offspring.

Article Sources
The Spruce Pets uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
  1. Díaz-Delgado J, Whitley DB, Storts RW, Heatley JJ, Hoppes S, Porter BF. The Pathology of Wobbly Hedgehog Syndrome. Veterinary Pathology. 2018;55(5):711-718. doi:10.1177/0300985818768033


  2. Ruszkowski JJ. Wobbly Hedgehog Syndrome (Whs): a review of knowledge and some practical suggestions about differential diagnosis. Medycyna Weterynaryjna. 2020;76(05):6397-2020.